Esculentoside A

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Esculentoside A 可以通过抑制 NF-κB 和丝裂原激活蛋白激酶信号通路来抑制 LPS 诱导的 ALI 中的炎症反应。

Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmune disease through modulation on T cell-mediated adaptive immunity. Esculentoside A may play significant roles in the treatment of BXSB mice through modulation of inflammatory cytokines, inhibition of renal cell proliferation and induction of apoptosis.

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Animal Model: BXSB miceDosage:20 mg/kg Administration:Intraperitoneal injection; 20 mg/kg; once a day; 4 weeks Result: Alleviated the renal damage of LN.

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Others

Other Targets

NF-κB

Others-Field

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65497-07-6

826.96

C42H66O16

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (120.92 mM)

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(-20℃)

With Ice Pack

≥ 2 years